McFate‐Smith 1991.
Methods | 2‐ to 4‐week single‐blind placebo run‐in; inclusion criteria= sitting DBP 95‐115 mm Hg after run‐in; 4‐week double‐blind treatment | |
Participants | All patients: n=202; mean age=70 years; baseline sitting SBP=177 mm Hg, DBP=103 mm Hg; Benazepril 2 mg BID: n=50; Benazepril 10 mg BID: n=50; Placebo: n=50 | |
Interventions | Benazepril 2 mg twice daily; Benazepril 10 mg twice daily; Placebo | |
Outcomes | Mean change from baseline in sitting SBP/DBP; BP measured 10‐14 h post‐dose | |
Notes | BP change reported; SD of change not reported, endpoint BP and SD not reported; imputed overall trial mean SD of change; BP data from Table 1, p. IV‐81; BP measurement device not reported; Jadad score=3; funding source= Ciba‐Geigy Inc. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |