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. 2019 Oct 7;6(11):e737–e749. doi: 10.1016/S2352-3018(19)30262-0

Figure 5.

Figure 5

Cross-protocol comparisons of HVTN 096, RV144, and HVTN 100 studies

(A) Comparison of V1/V2 antigens common across the three protocols at peak timepoints (with study groups of HVTN 096 pooled): AE.A244 V1V2 Tags 293F (matched), gp70_B CaseA_V1_V2 (not matched), and gp70_B CaseA2 V1/V2/169K (not matched). (B) Comparison of IgG responses to gp120 antigens across the three protocols at peak timepoints (with study groups of HVTN 096 pooled): Con 6 gp12/B and Con S gp140 CFI. Boxplots show the distribution of positive responses. Circles show positive responses; negative responses are shown as triangles. The proportion of positive responders at peak timepoints (2 weeks after the month 6 vaccination) are shown at the bottom of each panel. p.rate=p value for difference in response. p.mag=p value for difference in magnitude of response. HVTN=HIV Vaccine Trials Network. MFI=mean fluorescence intensity.