Table 3.

Longitudinal linear regression estimation using both the RE and GEE methods

	Crude (RE)	Adjusted (RE)	Crude (GEE)	Adjusted (GEE)
Amplitude	0.834	0.827	0.819	0.773
Down-slope	0.816	0.753	0.799	0.690
Up-slope	0.814	0.810	0.796	0.756
Period	0.037	0.025	0.022	0.015

In this table, the p-values associated to subjects with mutated KCNJ10 are shown. Two models have been made: one “Crude” including only KCNJ10, and one “Adjusted” in which gender, age and VPA were also included.

RE, random effects model; GEE, generalized estimating equations model; VPA, sodium valproate.