Table 4.
Leukotoxicity (200 ng/mL) in presence of Psidium guajava or O. vulgare EO alone or in combination after 2 h incubation in cultures of PMA-differentiated THP-cells. Result is expressed as percent viable cells in relation to control cells (100%) based on quantitative neutral red uptake analyses. Mean ± SD of triplicate analyses.
| Concentration (µL/mL) | Oil (%) | Guava (%) | Association oil and Guava (%) | p |
|---|---|---|---|---|
| 0 | 99.99± 0.93 * | 100 ± 0.93 | 100 ± 0.93 | <0.001 |
| 4 | 93.82 ± 3.13 * | 93.55 ± 0.98 | 96.27 ± 0.98 | <0.001 |
| 8 | 95.73 ± 0.31 * | 91.92 ± 2.72 | 106.33 ± 1.65 | <0.001 |
| 16 | 98.99 ± 0.41 * | 106.60 ± 6.14 | 90.01 ± 8.17 | <0.001 |
| 31 | 102.52 ± 1.22 * | 108.51 ± 10.02 | 105.79 ± 20.35 | <0.001 |
| 62 | 78.86 ± 3.86 * | 85.39 ± 7.24 | 93.55 ± 2.52 | <0.001 |
| 125 | 59.28 ± 1.72 * | 98.72 ± 6.81 | 84.30 ± 2.61 | <0.001 |
| 250 | −4.07 ± 0.31 * | 93.01 ± 4.31 | 98.99 ± 9.99 | <0.001 |
* Significant difference (p < 0.001).