Table 2.
The antitumor response of TS/A carcinoma after different treatment modalities.
| Group | n | DT (Days) AM ± SE | GD (Days) AM ± SE | CR | SC (Secondary Challenge) | ||
|---|---|---|---|---|---|---|---|
| n | % | n | % | ||||
| Control | 16 | 2.2 ± 0.2 | 0.0 | 0 | 0 | 0 | 0 |
| 3× EP | 11 | 2.8 ± 0.2 | 0.6 ± 0.2 | 0 | 0 | 0 | 0 |
| 3× pControl | 11 | 2.9 ± 0.7 | 0.7 ± 0.7 | 0 | 0 | 0 | 0 |
| 3× pMCAM | 9 | 2.1 ± 0.2 | −0.1 ± 0.2 | 0 | 0 | 0 | 0 |
| IR | 16 | 3.0 ± 0.3 | 0.8 ± 0.3 | 0 | 0 | 0 | 0 |
| 3× GET pControl | 14 | 6.3 ± 0.9 | 4.1 ± 0.9 | 0 | 0 | 0 | 0 |
| 3× GET pMCAM | 13 | 11.1 ± 0.8 | 8.9 ± 0.8 | 0 | 0 | 0 | 0 |
| 3× EP+IR | 16 | 13.9 ± 2.8 | 11.7 ± 2.8* | 3 | 18.8 | 0 | 0 |
| pControl+IR | 15 | 2.8 ± 0.2 | 0.6 ± 0.2 | 0 | 0 | 0 | 0 |
| pMCAM+IR | 16 | 3.6 ± 1.4 | 1.4 ± 1.4 | 0 | 0 | 0 | 0 |
| 3× GET pControl+IR | 13 | 24.4 ± 3.7 | 22.2 ± 3.7** | 1 | 7.7 | 0 | 0 |
| 3× GET pMCAM+IR | 15 | 30.9 ± 2.9 | 28.7 ± 2.9** | 4 | 26.7 | 0 | 0 |
AM: arithmetic mean; SE: standard error of arithmetic mean; DT: tumor doubling time; n: number of all mice in the group; GD: tumor growth delay; CR: complete response, tumor-free animal at day 100, % was calculated by dividing n of animals in complete response by n of animals in the corresponding group; SC: mice resistant to secondary challenge; * p < 0.05: statistically significant difference compared to groups: control, 3× EP, 3× pControl, 3× pMCAM, IR, pControl + IR, pMCAM + IR; ** p < 0.05- statistically significant difference compared to all other groups except between GET pMCAM + IR and GET pControl + IR.