Table 1.
Serum and Victoria lineage viruses. The designation for each post-vaccination serum (column 1) and year of vaccine receipt (column 2) are listed. Hemagglutination inhibition (HAI) titers toward IBV vaccine component (from [25]) are shown in columns 3 and 4. HAI titers (geometric mean from four replicates) for the sera toward the contemporary B/Colorado/06/2017 virus are in column 5. The number of passages used to attain the escape virus are shown and the name of each escape virus, which incorporates the serum name, are shown in the last two columns. HK330, B/Hong Kong/330/01; BR60, B/Brisbane/60/2008; CO_WT, B/Colorado/06/17; ND, not determined.
| Serum | Years Vaccinated | HK330 HAI Titer | BR60 HAI Titer | CO_WT HAI Titer | Number of Passages | Escape Virus |
|---|---|---|---|---|---|---|
| F09 | 2002, 2003 | 10 | ND | 8 | 4 | CO/F09 |
| M50 | 2002, 2003 | 40 | ND | 12 | 4 | CO/M50 |
| M74 | 2002, 2003 | 320 | ND | 22 | 3 | CO/M74 |
| M09 | 2010, 2011 | ND | 10 | 9 | 4 | CO/M09 |
| M56 | 2010, 2011 | ND | 40 | 11 | 3 | CO/M56 |
| F16 | 2010, 2011 | ND | 320 | 14 | 1 | CO/F16 |