. 2020 Mar 24;11(2):e00338-20. doi: 10.1128/mBio.00338-20

TABLE 3.

ABC transporter activity summary

Gene name	Resistance^a	Hypersusceptibility^a	% change for:
Gene name	Resistance^a	Hypersusceptibility^a	Ala-Nap efflux^b^,^d	R-6G efflux^b^,^d	R-6G efflux with FK506^c^,^d
abcA	POS, R-6G	—	+72	+169	−34
abcC	CLT, FLC, ITC, KTC, POS, R-6G, TEBZ, VRC	—	+158	+175	−61
abcF	CLT, ECON, FLC, ITC, KTC, MET, MCZ, PCLZ, POS, R-6G, TEBZ	AMB, CR, CW, NaCl	+121	+223	−51
abcG	—	—	+48	+62	−73
abcH	R-6G	CR	+35	+29	−99
abcI	FLC, R-6G	NaCl	+11	+73	0
WT/PDR5	CLT, FLC, ITC, KTC, MET, PCLZ, POS, R-6G, VRC	G418	+35	+356	−82

As determined by MIC or spot assays to differ from the S. cerevisiae ΔPDR5 mutant by >4-fold. —, MIC or spot assay value does not significantly differ from the S. cerevisiae ΔPDR5 mutant value.

Percent increase of efflux compared to the S. cerevisiae ΔPDR5 mutant.

Percent decrease in R-6G efflux in the presence of FK506 and GLC compared to GLC-only.

Based on efflux rates from 0 to 20 min.