TABLE 3.
Analysis of the types and distribution of allelic variation observed for multiple meningococcal isolates and multiple time points during persistent carriage
| Allelic variation typea | Incidence | Variable genes (carriers) |
|---|---|---|
| Sporadic | 35 | NEIS0212 (V51), pilQ (V51), pglA (V51), uvrA (V54), gltX (V59), rpoC (V59), NMB0830 (V59), NMB1114 (V59), NMB1220 (V59), sspA (V59), polA (V59) mutS (V69), NEIS1978 (V69), NEIS1339 (V93), NEIS0202 (V93), NEIS1009 (V93), pabBC (V93), NEIS1623 (V93), NEIS0202 (V96), secG (V96), iga (V96) mafB1 (V96), NEIS1640 (V96), pldA (V96), NEIS1708 (V96), hrpA (V96), yccA (V96), NMB0669 (V114), ligA (V114), NMB0409 (V117), NMB1288 (V138), NMB0424 (V138), pilG (V138), tspA (V222), NEIS2119 (V222) |
| Transient | 14 | pilU (V59, V96), NEIS0071 (V59), iga (V59, V96), clpA (V59), NMB0846 (V59), ilvL (V59), MTFMT (V96), mutS (V96), NMB1485 (V114), NMB0114 (V128), suhB (V128), NMB0274 (V138) |
| Putative fixation | 22 | argC (V51), argF (V54), ddl (V59), NEIS0498 (V59), mutS (V59), porB (V64, V124), NEIS0176 (V93), hemD (V93), NEIS1555 (V93), rplM (V93), NEIS0796 (V96), NEIS1329 (V96), tspA (V96), NEIS1978 (V96), hemK (V96), NEIS2450 (V96), NMB0920 (V114), dnaB (V117), NMB0439 (V128), aspC (V128), tbpB (V222) |
| Potential fixation | 11 | lbpA (V96), lbpB (V96), pilF (V96), porB (V117), pip (V222), bamC (V222), dapA (V222), NEIS0908 (V222), thiC (V222), NEIS2022 (V222), NEIS2522 (V222) |
a
Sporadic, occurring in only 1 tested isolate of 6 or more; transient, occurring at an intermediate time point or only in a subset of isolates; putative fixation, occurring in all isolates of the final time point; potential fixation, occurring in the majority of isolates of the final two time points.