Table 8.
Multiple logistic regression exploring the association between ivermectin thrice and once and seizure freedom during M9 to M12 of follow-up (as-treated analysis, group 1).
| Variables | OR | 95% CI | p-Value | |
|---|---|---|---|---|
| Ivermectin dose thrice vs once | 3.318 | 1.161 | 10.500 | 0.035 |
| Female vs male | 1.526 | 0.521 | 4.671 | 0.458 |
| Age | 1.061 | 0.967 | 1.177 | 0.248 |
| Weight (in kg) | 1.011 | 0.952 | 1.074 | 0.732 |
| Seizure frequency at baseline | 0.815 | 0.347 | 1.755 | 0.627 |
| Duration of epilepsy (years) | 0.681 | 0.291 | 1.553 | 0.380 |
| Microfilarial density at baseline * | 0.746 | 0.542 | 0.999 | 0.065 |
| Optimal vs sub-optimal AED adherence during last four months | 1.897 | 0.635 | 6.001 | 0.278 |
| >30 mg of AED increase (between M0 and M12) vs no increase | 0.201 | 0.063 | 0.581 | 0.006 |
OR: Odds ratio; CI: Confidence interval; AED: Antiepileptic drug; *: Log-transformed.