Table 2.
Imidazo[1,2-b][1,2,4,5]tetrazines MICs on M. smegmatis strains in liquid medium.
Compound | M. smegmatis Strains MICs, μg/mL | ||||||||
---|---|---|---|---|---|---|---|---|---|
mc2 155 | atR1c | atR2c | atR9c | atR14c | atR33c | 0641c | 1601c | 2087c | |
3a | 128 | 512 | 512 | 512 | 512 | 512 | 128 | 128 | 128 |
3c | 64 | >128 * | >128 * | >128 * | >128 * | >128 * | 64 | 64 | 64 |
3h | 128 | >256 * | >256 * | >256 * | >256 * | >256 * | 128 | 128 | 128 |
3n | 64 | 256 | 256 | 256 | 256 | 256 | 64 | 64 | 64 |
* The compounds were not soluble at higher concentrations; bacterial growth was observed at the stated concentrations.