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. 2020 Feb 28;9(3):166. doi: 10.3390/pathogens9030166

Table 2.

Imidazo[1,2-b][1,2,4,5]tetrazines MICs on M. smegmatis strains in liquid medium.

Compound M. smegmatis Strains MICs, μg/mL
mc2 155 atR1c atR2c atR9c atR14c atR33c 0641c 1601c 2087c
3a 128 512 512 512 512 512 128 128 128
3c 64 >128 * >128 * >128 * >128 * >128 * 64 64 64
3h 128 >256 * >256 * >256 * >256 * >256 * 128 128 128
3n 64 256 256 256 256 256 64 64 64

* The compounds were not soluble at higher concentrations; bacterial growth was observed at the stated concentrations.