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HC080/VID 411—definition of CD4+ T-cell epitopes in HIV-1 protein Pol. Expanded PBMCs from volunteer 411 were stimulated with truncated peptides (left) in ICS and the elicited production of IFN-γ (green) and TNF-α (orange) by CD4+ T cells was determined. Arrows in the graph and amino acids F, S and Y indicate the stimulatory peptide termini.
