Table A1.
Clinical and economic outcomes per 1000 internationally adopted children (IAC), by disease (CLIA serotesting).
| VPD | Strategy | Total Cost of the Strategy (Euro) | IAC 1 Protected (N) | Avoided Cases (N) | Possible Cases (N) | Cost Per Child Protected (Euro) |
|---|---|---|---|---|---|---|
| Measles | Comparator | 17,445.68 | 960.83 | 0.0501 | 0.0018 | 18.16 |
| Strategy 1 | 14,906.42 | 979.45 | 0.0509 | 0.0010 | 15.22 | |
| Strategy 2 | 25,452.38 | 989.50 | 0.0514 | 0.0005 | 25.72 | |
| Rubella | Comparator | 18,245.20 | 962.78 | 0.00507 | 0.00013 | 18.95 |
| Strategy 1 | 13,234.60 | 995.05 | 0.00518 | 0.00003 | 13.30 | |
| Strategy 2 | 25,452.38 | 995.13 | 0.00518 | 0.00003 | 25.58 | |
| Mumps | Comparator | 9482.39 | 915.02 | 0.0664 | 0.0067 | 10.36 |
| Strategy 1 | 16,145.01 | 941.90 | 0.0653 | 0.0038 | 17.14 | |
| Strategy 2 | 25,452.38 | 875.00 | 0.0639 | 0.0091 | 29.09 | |
| Varicella | Comparator | 23,945.44 | 930.43 | 3.5382 | 0.2688 | 25.74 |
| Strategy 1 | 17,151.46 | 970.66 | 3.6788 | 0.1282 | 17.67 | |
| Strategy 2 | 25,452.38 | 934.25 | 3.5566 | 0.2503 | 27.24 | |
| All VPDs together | Comparator | 69,118.72 | 3769.06 | 3.6598 | 0.2773 | 18.34 |
| Strategy 1 | 61,437.50 | 3887.05 | 3.8002 | 0.1330 | 15.81 | |
| Strategy 2 | 101,809.50 | 3793.88 | 3.6771 | 0.2600 | 26.84 |
Note: IAC 1 = Internationally adopted children; comparator = vaccine based on vaccination records; strategy 1 = vaccine based on serology; strategy 2 = vaccine to all IAC; VPDs= vaccine preventable diseases; CLIA= chemiluminescent immunoassay.