Table A5.
Clinical and economic outcomes per 1000 internationally adopted children (IAC) < 1 year of age (CLIA method).
| VPD | Strategy | Total Cost of the Strategy (Euro) | IAC 1 Protected (N) | Avoided Cases (N) | Possible Cases (N) | Cost Perchild Protected (Euro) |
|---|---|---|---|---|---|---|
| Measles | Comparator | 17,257.47 | 960.06 | 0.0474 | 0.0018 | 17.98 |
| Strategy 1 | 14,546.03 | 979.23 | 0.0482 | 0.0010 | 14.85 | |
| Strategy 2 | 25,452.38 | 989.50 | 0.0487 | 0.0005 | 25.72 | |
| Rubella | Comparator | 18,049.73 | 961.87 | 0.00512 | 0.00014 | 18.77 |
| Strategy 1 | 12,876.12 | 995.04 | 0.00523 | 0.00003 | 12.94 | |
| Strategy 2 | 25,452.38 | 995.13 | 0.00523 | 0.00003 | 25.58 | |
| Mumps | Comparator | 9425.43 | 915.16 | 0.0666 | 0.0067 | 10.30 |
| Strategy 1 | 14,062.55 | 950.72 | 0.0723 | 0.0040 | 14.79 | |
| Strategy 2 | 25,452.38 | 875.00 | 0.0641 | 0.0092 | 29.09 | |
| Varicella | Comparator | 23,918.71 | 930.37 | 3.5553 | 0.2703 | 25.71 |
| Strategy 1 | 17,030.59 | 970.96 | 3.6975 | 0.1282 | 17.54 | |
| Strategy 2 | 25,452.38 | 934.25 | 3.5741 | 0.2515 | 27.24 | |
| All VPDs together | Comparator | 68,651.33 | 3767.46 | 3.6744 | 0.2789 | 18.22 |
| Strategy 1 | 58,515.28 | 3895.95 | 3.8232 | 0.1332 | 15.02 | |
| Strategy 2 | 101,809.50 | 3793.88 | 3.6921 | 0.2612 | 26.84 |
Note: IAC 1 = Internationally adopted children; comparator = vaccine based on vaccination records; strategy 1 = vaccine based on serology; strategy 2 = vaccine to all IAC; VPDs= vaccine preventable diseases; CLIA= chemiluminescent immunoassay.