Table 5.
Factors associated with unsuccessful treatment outcome among MDR-TB patients who received STR from April 2016 to June 2018 in Vietnam.
| Factors | Total | Unsuccessful Outcome | RR | (95%CI) | aRR | (95%CI) | ||
|---|---|---|---|---|---|---|---|---|
| N | n | (%)# | ||||||
| Total | 302 | 43 | (14.2) | |||||
| Age in years | ||||||||
| 15–44 | 188 | 22 | (11.7) | ref | ref | |||
| 45–64 | 95 | 17 | (17.9) | 1.53 | (0.85–2.74) | 1.57 | (0.84–2.93) | |
| ≥ 65 | 19 | 4 | (21.0) | 1.80 | (0.69–4.68) | 2.97 | (1.22–7.22) * | |
| Gender | ||||||||
| Male | 224 | 35 | (15.6) | 1.52 | (0.74–3.14) | 1.31 | (0.71–2.44) | |
| Female | 78 | 8 | (10.3) | ref | ref | |||
| BMI | ||||||||
| Under weight (<18.5) | 113 | 15 | (13.3) | 1.10 | (0.54–2.23) | 0.98 | (0.46–2.06) | |
| Normal (18.5–22.9) | 99 | 12 | (12.1) | ref | Ref | |||
| Overweight/Obese (≥23.0) | 17 | 3 | (17.6) | 1.46 | (0.46–4.62) | 1.52 | (0.48–4.81) | |
| Missing | 73 | 13 | (17.8) | 1.47 | (0.71–3.03) | 1.82 | (0.93–3.57) | |
| TB category | ||||||||
| New | 113 | 13 | (11.5) | ref | ref | |||
| Previously treated | 175 | 26 | (14.9) | 1.29 | (0.69–2.41) | 1.22 | (0.65–2.28) | |
| Missing | 6 | 2 | (33.3) | 2.9 | (0.84–10.03) | 3.21 | (1.04–9.92) * | |
| HIV | ||||||||
| Positive | 3 | 2 | (66.6) | 4.82 | (2.04–11.34) | 7.14 | (3.51–15.65) * | |
| Negative | 253 | 35 | (13.8) | ref | ref | |||
| Unknown | 46 | 6 | (13.0) | 0.94 | (0.42–2.11) | 1.14 | (0.52–2.51) | |
| Year of enrolment | ||||||||
| 2016 | 99 | 20 | (20.2) | 1.76 | (0.95–3.27) | 1.79 | (0.99–3.25) | |
| 2017 | 72 | 8 | (11.1) | 0.97 | (0.43–2.18) | 0.90 | (0.40–1.99) | |
| 2018 | 131 | 15 | (11.4) | ref | ||||
| Culture | ||||||||
| Negative | 61 | 6 | (9.8) | ref | ||||
| Positive | 199 | 33 | (16.6) | 1.69 | (0.74–3.83) | 2.39 | (1.09–5.24) * | |
| Unknown | 42 | 4 | (9.5) | 0.97 | (0.29–3.22) | 1.44 | (0.41–4.99) | |
#Row percentage.RR, risk ratio; aRR– adjusted risk ratio; CI, confident interval; BMI, body mass index; * statistically significant.