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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Binding of human A. actinomycetemcomitans to buccal epithelial cells (BECs). A. actinomycetemcomitans binds to BECs from Old World primates but not from New World primates. Mutation of the aae gene significantly reduces binding in these primates.