FIG 7.
Representative images of lung tissues from mice receiving PBS (A), UV-inactivated MERS-CoV (B), or PIV5-MERS-S (C) treatment, followed by infection with MERSMA6.1.2. Images obtained from tissues at 3 days after MERSMA6.1.2 infection. Compared to PBS or PIV5-MERS, perivascular eosinophilic infiltration (arrows) in UV-MERS-treated mice was greatly increased. n = 3 to 4 mice/group. (D) Graph representing eosinophil infiltration in the lung tissues of mice from groups shown in panels A to . * denotes P < 0.009, Dunn’s posttest. Other group comparisons were not significant. (E) Graph representing hyaline membranes in the lung tissues of mice from groups shown in panels A to C. * denotes P < 0.0065, Dunn’s posttest. Other group comparisons were not significant.