Table 3.
Associations of podocalyxin expression in renal tissues and urinary podocalyxin/urine creatinine ratio with the clinicopathological characteristics of patients with diabetic nephropathy.
| Renal podocalyxin expression | Urinary podocalyxin/urinary creatinine | |||
|---|---|---|---|---|
| Correlation coefficient | P value | Correlation coefficient | P value | |
| Age (years) | -0.127 | 0.489 | 0.222 | 0.221 |
| Diabetes course (months) | -0.273 | 0.137 | 0.162 | 0.376 |
| Nephropathy course (months) | -0.155 | 0.389 | 0.012 | 0.949 |
| Mean arterial pressure (mmHg) | -0.151 | 0.408 | 0.072 | 0.649 |
| HbA1c (%) | -0.706 | <0.001 | 0.534 | 0.002 |
| FPG (mmol/L) | -0.206 | 0.257 | 0.209 | 0.25 |
| Triglycerides (mmol/L) | -0.203 | 0.264 | 0.304 | 0.091 |
| Cholesterol (mmol/L) | -0.112 | 0.541 | 0.102 | 0.578 |
| Albumin (g/L) | 0.559 | 0.001 | -0.629 | <0.001 |
| NAG (U/L) | -0.205 | 0.260 | 0.343 | 0.05 |
| Urine protein (g/24 h) | -0.513 | 0.003 | 0.764 | <0.001 |
| Serum creatinine (μmol/L) | -0.629 | <0.001 | 0.614 | <0.001 |
| eGFR | 0.604 | <0.001 | -0.677 | <0.001 |
| Glomerular grade | -0.108 | 0.556 | 0.268 | 0.138 |
| IFTA | -0.325 | 0.069 | 0.49 | 0.004 |
| Renal interstitial inflammation | -0.547 | 0.001 | 0.562 | 0.001 |
| Renal arteriosclerosis | -0.386 | 0.029 | 0.441 | 0.011 |
| Podocalyxin | -0.691 | <0.001 | -0.695 | <0.001 |
eGFR: estimated glomerular filtration rate; FPG: fasting plasma glucose; HbA1c: glycated hemoglobin; IFTA: tubular atrophy and interstitial fibrosis; NAG: N-acetyl-beta-D-glucosaminidase.