TABLE 2.

MIC assessments with β-lactamase inhibitor combinations

Drug	MIC (μg/ml)
	AJ218 plus empty vector			AJ218 ΔK35 ΔK36 plus empty vector
	No inhibitor	Tazobactama	Avibactamb	No inhibitor	Tazobactama	Avibactamb
Ampicillin	8,192	4	4	8,192	1,024	32
Cefazolin	8	0.5	1	1,024	256	16
Ceftazidime	0.5	0.125	0.25	4	1	1
Ceftriaxone	0.0625	0.03125	0.0625	0.5	0.5	0.5
Cefotaxime	0.0625	0.03125	0.0625	0.5	0.5	0.5
Imipenem	0.5	0.25	0.25	0.5	0.25	0.5
Meropenem	0.03125	0.015625	0.03125	0.5	0.5	0.0625
Ertapenem	0.015625	0.008	0.015625	4	2	1

^aTazobactam was used at a final concentration of 64 μg/ml.

^bAvibactam was used at a final concentration of 4 μg/ml.