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. 2020 Apr 8;11:457. doi: 10.3389/fphar.2020.00457

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Copyright © 2020 Zhang, Wang, Zhou, Yang, Xu, Xu, Xu, Yan, Cheng, Li and Qin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Terphenyllin inhibits pancreatic cancer cell migration and invasion in vitro. (A) Transwell migration assay was performed in Panc1 and HPAC cells with or without terphenyllin treatment. Representative microscopic images of cells that migrated through the transwell. (B) The quantitation of cells that migrated through the transwell in the migration assay. (C) Transwell Matrigel invasion assay was performed in Panc1 and HPAC cells with or without terphenyllin treatment. Representative microscopic images of cells that invaded through the transwell. (D) Quantitation of cells that invaded through the transwell in the Matrigel invasion assay. Data are representative of at least three experiments. (*p < 0.05, **p < 0.01).