Table 3.
List of the 5 overlapping genes in which analysis of a higher number of homologs revealed that they undergo asymmetric evolution (chi-square value > 3.84; 1 degree of freedom)..
| Genome ac. numbera | Virus speciesb | Overlapping gene (protein products) | Number of conserved and non-conserved amino acid positions in the alignmentc | Chi-square value | Most variable protein |
|---|---|---|---|---|---|
|
NC_003809 (EU919669, NC_003568, NC_003834, NC_003547, NC_009538, NC_011809) |
Spinach latent virus (Lilac ring mottle virus, Elm mottle virus, Tulare apple mosaic virus, Tomato necrotic streak virus, Citrus leaf rugose virus, Citrus variegation virus, Asparagus virus 2) |
RNA-dependent RNA polymerase (2a)/2b protein | 2a: 7, 36 (16.3%) 2b: 19, 24 (44.2%) |
6.67 (P = 0.01) | RNA-dependent RNA polymerase (2a) |
|
NC_004146 (NC_004142, KU754529) |
Flock house virus (Boolarra virus, Newington virus) |
RNA-dependent RNA polymerase(A)/B2 protein | A: 53, 46 (53.5%) B2: 72, 28 (72%) |
6.49 (P = 0.01) | RNA-dependent RNA polymerase (A) |
|
NC_001747 (NC_006265, NC_034265, NC_016038, NC_031747, NC_008249, NC_030225) |
Potato leafroll virus (Carrot red leaf virus, Tobacco virus 2, Brassica yellows virus, White clover mottle virus, Chickpea chlorotic stunt virus, Pepo aphid-borne yellows virus) |
capsid protein (P3)/movement protein (P4) | P3: 38,52 (42.2%) P4: 19, 71 (21.1%) |
8.32 (P = 0.004) | movement protein (P4) |
|
NC_004674 (NC_000869, KM978186, NC_003708, NC_030310) |
East African cassava mosaic virus (Tomato yellow leaf curl Thailand virus, Euphorbia yellow leaf curl virus, Watermelon chlorotic stunt virus, Cotton yellow mosaic virus) |
transcriptional activator (TrAP, AC2 protein)/replication enhancer (Ren, AC3 protein) | AC2: 28, 58 (32.6%) AC3: 46, 51 (52.9%) |
6.49 (P = 0.01) | transcriptional activator (TrAP, AC2 protein) |
|
NC_003977 (HPBVCG, NC_028129, NC_020881) |
Hepatitis B virus isolate USA (Chimpanzee hepatitis B virus, Woolly monkey hepatitis B virus, Long-fingered bat hepatitis B virus) |
X protein/polymerase (P) | X: 36, 40 (47.4%) P: 50, 27 (64.9%) |
4.11 (P = 0.04) | X protein |
a
Parenthesis indicates the ac. number of the homologs.
b
Parenthesis indicates the source of the homologs.
c
Parenthesis indicates the percent of the amino acid identity.