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. 2020 Apr 13:1–12. doi: 10.1080/1040841X.2020.1739001

Table 2.

Key interacting residues between RBD of spike protein of different corona viruses and host receptor ACE2 of human, bat, mouse civet and different avian species (modified from Dong et al. 2020).

41 42 45 79 82 83 90 325 329 353 Amino Acid (aa) position relative to human ACE2
Y E L N R F D E T K Gallas ACE2
Y E L N N F D E K K Anas ACE2
Y E L N N F D E K K Tadorna ACE2
Y E L N S F D E K K Anser ACE2
Y Q V L T Y D Q E K Civet ACE2
Y Q L T S F T Q A H Mouse ACE2
Y Q L I N F N P T H Rat ACE2
H E L L T Y N P N K Bat ACE2
Y Q L L M Y N Q E K Human ACE2
Y484 Y436 Y484 L472 L472 Y475 T402 R426 R426 Y491 Human SARS
Y485 Y437 Y485 F473 F473 Y476 T403 R427 R427 Y492 BatSARS-likeCoV-WIV1
Q498 Y449 Q498 F486 F486 Y489 T415 N439 N439 Y455 SARS-CoV-2
N474 G439 N474 E462 E462 V465 T410 A434 A434 Y481 Bat SARS-like CoV SL-CoVZXC21
N473 G435 N471 G459 G459 V462 T406 A430 A430 Y481 Bat SARSr-CoV HKU3-1

The table is shaded to make its representation more attractive.