Table 1.
Demographic, clinical, and outcome data for hospitalized patients with laboratory confirmed influenza based on the recovery of influenza virus RNA from the air.
| Negative air* (n = 10) | Positive air (n = 6) | Overall (n = 16) | P-value | |
|---|---|---|---|---|
| Age-years, median (range) | 58 (49–92) | 68 (28–80) | 58.5 (28–92) | 0.91 |
| Sex, n male (%) | 4 (40.0) | 1 (16.7) | 5 (31.3) | 0.59 |
| Number of symptoms, mean (SD) | 7 (2.5) | 9 (2.5) | 8 (2.5) | 0.34 |
| Documented fever, n (%) | 6 (60.0) | 6 (100.0) | 12 (75) | 0.23 |
| Pharyngitis, n (%) | 2 (20.0) | 3 (50.0) | 5 (31.3) | 0.30 |
| Need for O2 therapy, n (%) | 5 (50.0) | 4 (66.7) | 9 (56.3) | 0.63 |
| Influenza vaccination, n (%)† | 5 (55.6) | 3 (50.0) | 8 (53.3) | 1.0 |
| Past or current smoker, n (%)† | 6 (66.7) | 3 (50.0) | 9 (60) | 0.62 |
| Chest X-ray changes, n (%) | 4 (40.0) | 4 (66.7) | 8 (50) | 0.61 |
| Mid-turbinate swab viral load, log10 copies/mL mean (SD)‡ | 3.8 (2.7) | 4.8 (1.6) | 4.1 (2.4) | 0.54 |
| Community-acquired influenza, n (%) | 7 (70.0) | 4 (66.7) | 11 (68.8) | 1.0 |
| Influenza A virus, n (%) | 7 (70.0) | 6 (100) | 13 (81.3) | 0.25 |
| H1N1, n (%) | 5 (50.0) | 4 (66.7) | 9 (56.3) | 0.63 |
| H3N2, n (%) | 2 (20.0) | 2 (33.3) | 4 (25) | 0.60 |
| Influenza B virus, n (%) | 3 (30.0) | 0 (0) | 3 (18.8) | 0.25 |
| Length of stay – days, mean (range) | 15.3 (3–56) | 15.8 (3–47) | 15.5 (3–56) | 0.79 |
| Admission to ICU, n (%) | 2 (20.0) | 0 (0) | 2 (12.5) | 0.5 |
*
Group includes 9 patients with negative air samples and 1 with insufficient quantity for PCR.
†
n = 15; unable to complete interview for one participant in negative air group.
‡
n = 14; insufficient sample for MT viral load for two participants with positive air samples.