Table 2.
Frequency of women with depression±, and case-identification using two methods* on the PHQ-2
Pregnancy | Postpartum | |||
---|---|---|---|---|
Baseline n = 303 |
36-weeks n = 275 |
6-weeks n = 252 |
26-weeks n = 227 |
|
n | n | n | n | |
% | % | % | % | |
(95% CI) | (95% CI) | (95% CI) | (95% CI) | |
Probable major depression± | 7 | 5 | 14 | 14 |
2.3 | 1.8 | 5.6 | 6.2 | |
(0.9–4.7) | (0.6–4.2) | (3.1–9.2) | (3.4–10.1) | |
At least probable minor depression± |
12 4.0 |
12 4.4 |
33 13.1 |
32 14.1 |
(2.1–6.8) | (2.3–7.5) | (9.2–17.9) | (9.9–19.3) | |
PHQ-2 total score ≥ 2 | 49 | 58 | 50 | 35 |
16.2 | 21.1 | 19.8 | 15.4 | |
(12.2–20.8) | (16.4–26.4) | (15.1–25.3) | (11.0–20.8) | |
PHQ-2 total score ≥ 3 | 14 | 20 | 19 | 10 |
4.6 | 7.3 | 7.5 | 4.4 | |
(2.6–7.6) | (4.5–11.0) | (4.6–11.5) | (2.1–8.0) | |
PHQ-2 Screen positive | 103 | 118 | 83 | 77 |
33.9 | 42.9 | 32.9 | 33.9 | |
(28.7–39.6) | (37.0–49.0) | (27.2–39.1) | (27.8–40.5) | |
Anhedoniaa (no depressed mood) | 80 | 96 | 61 | 52 |
26.4 | 34.9 | 24.2 | 22.9 | |
(21.5–31.8) | (29.3–40.9) | (19.1–30.0) | (17.6–28.9) | |
Depressed moodb (no anhedonia) | 68 | 71 | 68 | 57 |
22.4 | 25.8 | 27.0 | 25.1 | |
(17.9–27.6) | (20.8–31.4) | (21.6–32.9) | (19.6–31.3) | |
Depressed mood and anhedoniac | 45 | 49 | 46 | 32 |
14.9 | 17.8 | 18.3 | 14.1 | |
(11.0–19.4) | (13.5–22.9) | (13.7–23.6) | (9.9–19.3) |
95% CI: 95% confidence interval for a sample proportion with binomial (Clopper Pearson) exact
±Probable major depression: EPDS cut-off score ≥ 15 during pregnancy and ≥ 13 postpartum; At least probable minor depression: EPDS cut-off score ≥ 13 in pregnancy and ≥ 10 postpartum
*PHQ-2: Total score method with two cut-points (≥ 2 and ≥ 3); Categorical method: Screen positive to either Question 1 OR Question 2
**PHQ-2 Question completion: Categories of positive responses on PHQ-2 questions
aPositive response to PHQ-2 Question 1 and negative response on question 2
bPositive response to PHQ-2 Question 2 and negative response to question 1
cPositive response to PHQ-2 Question 1 and question 2