Table 3.

Visit schedule

	Selection visit (from − 3 months to day 0)	Baseline visit (day 0)	Treatment visit (day 7 ± 2)	Treatment visit (day 15 ± 3)	Treatment visit (day 28 ± 4)	End of treatment visit (day 60 ± 7)	Side effect visit (not scheduled)	Follow-up visit (months 4, 6, and 8)	Final visit (month 12)
Informed consent	x
Demographic data	x
Pathological background	x
Toxic habits	x
Chagas disease history	x
Concomitant medication	x	x	x	x	x	x	x	x	x
Directed anamnesis	x	x	x	x	x	x	x	x	x
Physical examination	x	x	x	x	x	x	x	x	x
Pregnancy test		x
Hematology	x		x	x	x	x	x
Biochemistry	x		x	x	x	x	x
HLA	x
Chest x-ray	x
EKG	x
PK				x		x	x
Serology	x								x
PCR	x		x	x	x	x		x	x
Other complementary tests	x
Adverse events		x	x	x	x	x	x
Randomization	x
Study medication		x	x	x	x	x

Abbreviations: EKG Electrocardiogram, HLA Human leukocyte antigen, PCR Polymerase chain reaction, PK Pharmacokinetics