Table 4.
Diagnostic performance indices of ELF for identifying LRE using thresholds with sensitivity and specificity of 80, 85 and 90%. Data are presented showing ELF thresholds with sensitivity and specificity values of 80, 85 and 90%, with data-derived diagnostic accuracy (proportion of true positives and true negatives), misclassification rate (proportion of false negatives and false positives) and the rate of indeterminate cases (ELF score between the thresholds)
| Sensitivity and specificity values | ELF thresholds | Sensitivity (%) | Specificity (%) | Diagnostic accuracy (%) | Misclassification rate (%) | Indeterminate (%) |
|---|---|---|---|---|---|---|
| Recruitment samples | ||||||
| 80% | 8.350 | 81.0 | 19.1 | 26.0 | 19.7 | 54.3 |
| 9.425 | 39.7 | 80.0 | ||||
| 85% | 8.270 | 84.5 | 16.5 | 26.0 | 19.7 | 54.3 |
| 9.750 | 27.6 | 85.2 | ||||
| 90% | 8.160 | 91.4 | 14.8 | 26.0 | 19.7 | 54.3 |
| 9.895 | 24.1 | 90.4 | ||||
| Second subsequent samples | ||||||
| 80% | 9.365 | 80.4 | 34.8 | 36.4 | 19.1 | 44.5 |
| 10.255 | 41.1 | 80.9 | ||||
| 85% | 8.975 | 85.7 | 14.8 | 36.4 | 19.1 | 44.5 |
| 10.540 | 28.6 | 86.1 | ||||
| 90% | 8.945 | 89.3 | 13.9 | 56.6 | 28.3 | 15.1 |
| 10.835 | 17.9 | 90.4 | ||||
ELF enhanced liver fibrosis