Table 1.
Cox regression analysis of clinical and DCE-MRI–derived parameters
Univariate | Multivariate | |||||
---|---|---|---|---|---|---|
Disease-free survival | Overall survival | Disease-free survival | Overall survival | |||
p value | p value | p valuesa | p valuesa | |||
Tumor volume | 0.026 | 0.019 | 0.49 | 0.69 | 0.18 | 0.76 |
FIGO stage | 0.0057 | 0.017 | 0.065 | 0.055 | 0.099 | 0.091 |
Lymph node status | 0.13 | 0.36 | 0.73 | 0.84 | 0.81 | 0.60 |
Tumor histology | 0.30 | 0.31 | – | – | – | – |
Patient age | 0.30 | 0.17 | – | – | – | – |
35p-Ktrans | 0.15 | 0.047 | 0.20 | – | 0.057 | – |
RV-Ktrans | 0.00033 | < 0.00001 | – | 0.026 | – | 0.0015 |
Values of p < 0.05 are highlighted in bold
ap values refer to multivariate regression analyses including tumor volume, FIGO stage, lymph node status, and either
35p-Ktrans or RV-Ktrans
35p-Ktrans, the value of Ktrans at the 35 percentile of the Ktrans frequency distribution of a tumor
RV-Ktrans, the tumor subvolume with Ktrans values < 0.13 min−1