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. 2020 Apr 15;8:26. doi: 10.1186/s40560-020-00442-7

Table 2.

Duration of meropenem and concomitant antimicrobial therapy

Standard-dose meropenem (n = 38) High-dose meropenem (n = 38) P value
Day of meropenem therapy, median (IQR) 6 (3–16) 5 (3–21) 0.035*
Concomitant antimicrobial therapy, n (%) 16 (42.1) 19 (50) 0.646
 Colistin, n (%) 3 (18.8) 2 (10.5) 0.642
 Vancomycin, n (%) 7 (43.8) 6 (31.6) 0.503
 Cotrimoxazole, n (%) 1 (6.3) 4 (21.1) 0.347
 Levofloxacin, n (%) 0 (0) 3 (15.8) 0.234
 Amikacin, n (%) 4 (25) 3 (15.8) 0.677
 Azithromycin, n (%) 1 (6.3) 2 (10.5) 1.000
 Oseltamivir, n (%) 2 (12.5) 2 (10.5) 1.000
De-escalation, n (%) 21 (55.3) 25 (65.8) 0.436

*Statistically significant difference