Table 2.
Duration of meropenem and concomitant antimicrobial therapy
| Standard-dose meropenem (n = 38) | High-dose meropenem (n = 38) | P value | |
|---|---|---|---|
| Day of meropenem therapy, median (IQR) | 6 (3–16) | 5 (3–21) | 0.035* |
| Concomitant antimicrobial therapy, n (%) | 16 (42.1) | 19 (50) | 0.646 |
| Colistin, n (%) | 3 (18.8) | 2 (10.5) | 0.642 |
| Vancomycin, n (%) | 7 (43.8) | 6 (31.6) | 0.503 |
| Cotrimoxazole, n (%) | 1 (6.3) | 4 (21.1) | 0.347 |
| Levofloxacin, n (%) | 0 (0) | 3 (15.8) | 0.234 |
| Amikacin, n (%) | 4 (25) | 3 (15.8) | 0.677 |
| Azithromycin, n (%) | 1 (6.3) | 2 (10.5) | 1.000 |
| Oseltamivir, n (%) | 2 (12.5) | 2 (10.5) | 1.000 |
| De-escalation, n (%) | 21 (55.3) | 25 (65.8) | 0.436 |
*Statistically significant difference