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. 2020 Apr 15;8:26. doi: 10.1186/s40560-020-00442-7

Table 4.

Pharmacodynamic target of the time above the minimum inhibitory concentration

MIC (mg/L) Standard-dose meropenem (n = 8) High-dose meropenem (n = 10)
Identified MIC, n 3 5
• Achievement of 40%T>MIC, n (%) 3 (100%) 5 (100%)
• Achievement of 100%T>MIC, n (%) 2 (66.7%) 5 (100%)
MIC = 8, n 8 10
• Achievement of 40%T>MIC, n (%) 5 (62.5%) 9 (90%)
• Achievement of 100%T>MIC, n (%) 2 (25%) 4 (40%)

MIC minimum inhibitory concentration, %T>MIC percent of the time of antibiotic concentrations above the minimum inhibitory concentration