Fig. 1.

Overall distribution of bacterial phyla and classes in the gut microbiome of controls, individuals who met full Sjögren’s criteria (SDE) and those that did not (NDE). a All three study groups exhibit a Firmicutes-Bacteroidetes dominated microbiome, with significant presence of Actinobacteria and Proteobacteria. b Bacteroidetes-Firmicutes ratio shows an upward trend for the SDE group, but it is statistically insignificant. c Dominant representative bacterial classes among all study subjects across the three study groups