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. 2018 Oct 26:499–515. doi: 10.1016/B978-0-12-805306-5.00020-1

Figure 20.4.

Figure 20.4

Chronic progressive nephropathy in a naked mole-rat.

Renal tubules are variably ectatic, atrophied, degenerate, necrotic, and replaced by collagenous fibrous tissue. Within the interstitium are accumulations of mononuclear cells (primarily lymphocytes and fewer macrophages). There is also sclerosis of glomeruli and periglomerular fibrosis.