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. 2017 Feb 17:805–907.e1. doi: 10.1016/B978-0-323-35775-3.00014-X

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Copyright © 2017 Elsevier Inc. All rights reserved.

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Figure 14-51 — Opportunistic Angioinvasive Fungi.

Fungi such as Absidia corymbifera, Rhizomucor pusillus, and Rhizopus arrhizus and fungi in the genus Aspergillus, such as Aspergillus niger, can invade blood vessels (angiotropic) and cause vascular necrosis and infarcts in the central nervous system. Note the vasculitis, hemorrhage, and disruption of the vessel and the fungal hyphae in the lumen (arrows). H&E stain. Inset, Fungal hyphae in the lumen of a blood vessel (arrow). H&E stain.

(Courtesy Dr. A.D. Miller, College of Veterinary Medicine, Cornell University. Inset courtesy Dr. J.F. Zachary, College of Veterinary Medicine, University of Illinois.)