Figure 14-77.

Hemangiosarcoma, Metastatic, Brain, Formalin-Fixed, Transverse Section at the Level of the Thalamus, Dog.

Note the prominent hematogenous metastases, which appear as black nodules of various sizes distributed throughout the brain, sometimes at the gray matter–white matter interface. In an unfixed (fresh) specimen the nodules would be red to dark red. Black nodules in a fresh specimen would be consistent with metastatic melanoma.

(Courtesy Dr. M.D. McGavin, College of Veterinary Medicine, University of Tennessee.)