Figure 14-106.

Pyogranulomatous Vasculitis, Feline Infectious Peritonitis (FIP), Cat.

A, Periventricular white matter (arrows) beneath the fourth ventricle (between the medullary vellum and medulla). The pyogranulomatous inflammation that occurs with FIP causes vascular and perivascular injury, vasogenic edema, and parenchymal disruption. H&E stain. B, A higher magnification of A. Ventriculitis and ependymitis are evident. Note the prominent perivascular cuffs of small mononuclear cells and macrophages. H&E stain. Inset, Higher magnification of B. H&E stain.

(Courtesy Dr. J.F. Zachary, College of Veterinary Medicine, University of Illinois.)