Table 14-8.

Hypomyelinogenesis and Dysmyelination in Animals

Species	Breed	Disease Designation	Genetic Cause	Infectious Cause	Metabolic Cause
Bovine	All breeds	Bovine virus diarrhea (dysmyelination)		Bovine virus diarrhea (pestivirus)
	Charolais	Progressive ataxia	Suspected
Ovine	All breeds	Border disease (hypomyelinogenesis-dysmyelination)		Border disease virus (pestivirus)
Porcine	Landrace	Congenital tremor (myelin agenesia)	Sex-linked recessive
	Saddleback	Congenital tremor	Autosomal recessive
	Chester-white	Myoclonia congenita	Autosomal recessive	Suspected
	All breeds	Congenital tremor (dysmyelinogenesis and cerebellar hypoplasia)		Classic swine fever (pestivirus)
	All breeds	Congenital tremor (dysmyelinogenesis)		Unknown virus suspected
	All breeds	Congenital ataxia and tremor (hypomyelinogenesis and cerebellar hypoplasia)			Trichlorfon (acaricide)
Canine	Dalmatian	Hypomyelinogenesis
	Chow Chow	Dysmyelination	Suspected
	Springer spaniel	Shaking pups (hypomyelination)	Sex-linked recessive
	Samoyed	Tremor (hypomyelination)	Suspected
	Lurcher	Tremor syndrome (hypomyelination)
	Weimaraner	Hypomyelination	Suspected