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. 2020 Apr 15;220:1–13. doi: 10.1016/j.trsl.2020.04.007

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Fig 8 — Demonstration of co-localization of complement components with SARS-CoV2 spike glycoprotein in the lung of Case 1. A, Striking deposition of C4d within the interalveolar septa of the lung was first demonstrated by DAB staining. Using NUANCE software the C4d image appears green (B) while the SARS-CoV2 spike protein appears red (C). D, A merged image shows a significant degree of C4d and SARS-CoV2 co-localization, as revealed by intense yellow staining. E–H, A similar pattern was observed using an anti-C5b-9 reagent whose image appears green, with a significant degree of C5b-9 and SARS-CoV2 co-localization, as revealed by intense yellow staining.