Table 4.
Univariate and multivariate analyses of prognostic variables for disease-free survival in patients with hepatitis B virus-related hepatocellular carcinoma.
| Variable | Univariate analysis |
Multivariate analysis |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | Statistical significance | HR | 95% CI | Statistical significance | |
| Age | 1.001 | 0.991, 1.012 | NS | |||
| Sex | 0.972 | 0.670, 1.594 | NS | |||
| CTP score | 0.662 | 0.221, 0.976 | P = 0.037 | |||
| HBV DNA | 0.495 | 0.330, 1.109 | NS | |||
| HBeAg status | 1.230 | 1.065, 1.692 | P = 0.021 | |||
| AFP level | 1.291 | 1.061, 2.182 | P = 0.015 | 1.210 | 1.115, 1.692 | P = 0.029 |
| Platelet count | 1.211 | 1.067, 1.877 | P = 0.027 | |||
| Total bilirubin | 1.159 | 0.698, 1.912 | NS | |||
| LS changes | 1.530 | 1.051, 2.248 | P = 0.035 | 1.521 | 1.074, 2.081 | P = 0.040 |
AFP, α-fetoprotein; CTP, Child–Turcotte–Pugh score; HBeAg, hepatitis B e antigen; HBV, hepatitis B virus; LS, liver stiffness; HR, hazard ratio; CI, confidence interval.
NS, no statistically significant correlation (P > 0.05; Cox proportional hazards).