Figure 6-19.

Uroperitoneum. Dog.

A, The fluid contained a high number of neutrophils, many of which appeared similar to this “ragged” cell. Urine acts as a chemical irritant, causing karyolytic changes to cells. (Wright-Giemsa; HP oil.) B, Cytospin preparation of abdominal fluid with a cluster of reactive mesothelial cells and one karyorrhectic and several karyolytic neutrophils. (Modified Wright; HP oil.) C, Sedimented fluid from same case as B. Several vacuolated macrophages along with mildly karyolytic neutrophils against a background of erythrocytes. Elevated fluid creatinine confirmed the suspicion of uroperitoneum.

(Courtesy of Rose Raskin, A, University of Florida; B-C, Purdue University.)