Figure 6-29.

Neoplastic effusion. Pleural. B-cell lymphoma. Cat. Same case A-B.

A, Cytocentrifuged specimen demonstrating marked pleomorphism of round cells. Some cells have multiple nuclei and irregularly shaped nuclei. Nucleoli are usually large and multiple. There is surface blebbing on several cells, which may be mesothelial in origin. (Modified Wright; HP oil.) B, All large round cells are positively stained for the CD79a antigen in this sediment smear of pleural fluid supporting a B-cell neoplasm. CD3 antigen was absent on all cells (not shown). (CD79a antibody; HP oil.)

(A and B, Courtesy of Rose Raskin, Purdue University.)