Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Genes and encoded proteins in polycystic diseases of kidney and liver
| Disorder | Gene | Product | Localized in cilium |
|---|---|---|---|
| ARPKD | PKHD | Fibrocystin/polyductin | Yes |
| ADPKD |
PKD1 | Polycystin 1 | Yes |
| PKD2 | Polycystin 2 | Yes | |
| PCLD | PRKCSH | β-subunit of glucosidase II | No |
| SEC63 | Component of translocon in endoplasmic reticulum | No | |
ARPKD, autosomal recessive polycystic kidney disease; ADPKD, Autosomal dominant polycystic kidney disease; PCLD, polycystic liver disease without kidney abnormalities.
