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. 2017 Feb 17:724–804.e2. doi: 10.1016/B978-0-323-35775-3.00013-8

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Copyright © 2017 Elsevier Inc. All rights reserved.

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Figure 13-31 — Leukemia, Canine Blood Smears.

A, Acute myeloid leukemia. A dog with acute myelomonocytic leukemia has a marked leukocytosis (52,200 white blood cells/µL) with myeloid blasts (arrows) differentiating into dysplastic neutrophils (arrowheads) and monocytes (m). Modified Wright's stain. B, Chronic myeloid leukemia. A dog with chronic myelomonocytic leukemia (arrows) has a marked leukocytosis (138,300 white blood cells/µL) with a predominance of mature neutrophils (105,108/µL) and monocytes (26,277/µL). Wright-Giemsa stain. C, Acute lymphoblastic leukemia. Note the large lymphoid cells with immature (fine) chromatin and nucleoli (arrows). The dog also had pancytopenia due to neoplastic myelophthisis. Modified Wright's stain. D, Chronic lymphocytic leukemia (CLL). Small lymphocytes predominate in CLL. The neoplastic lymphocytes have clumped chromatin and no to rare nucleoli (arrows). Most canine CLLs are of T lymphocyte origin with a granular phenotype. Modified Wright's stain.

(Courtesy Dr. K.M. Boes, College of Veterinary Medicine, Virginia Polytechnic Institute and State University.)