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. 2017 Feb 17:724–804.e2. doi: 10.1016/B978-0-323-35775-3.00013-8

Figure 13-40.

Figure 13-40

Structure of the Marginal Zone in the Splenic Follicle.

Antigens, bacteria, particles, and other material enter the follicle via the central arteries and reach the marginal sinus, where they are phagocytized by macrophages of the marginal zone. Once captured by these macrophages, blood-borne antigens are processed and presented to the lymphocytes within the white pulp.