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Canine distemper virus bronchointerstitial pneumonia and encephalitis in two tigers.
(A) Alveoli are lined by plump Type II pneumocytes and syncytial cells with characteristic intracytoplasmic and intranuclear inclusion bodies. Alveolar lumens contain numerous foamy macrophages and sloughed epithelial cells. (B) Multiple neurons and astrocytes contain eosinophilic, intranuclear inclusion bodies with mild non-suppurative, lymphoplasmacytic inflammation.
