Table 4-5.
Examples of Positive and Negative Interference on Biochemistry Analytes Induced by Sample Hemolysis
| Analyte | Effect of Hemolysis* |
|---|---|
| Alanine transaminase | Minimal effect |
| Alkaline phosphatase | Increased |
| Bilirubin | Increased |
| Chloride | Decreased |
| Creatinine | Increased |
| Inorganic phosphate | Increased |
| Lipase | Decreased |
| pH | Decreased |
| Potassium | No detectable effect |
| Total calcium | Increased |
| Total protein | Increased |
| Urea nitrogen | Increased |
Type and degree of interference vary among different testing modalities unique to individual laboratories or in-hospital biochemistry analyzers.