Table 4.3.
Analyte | Units | Sprague-Dawleyb |
Fisher 344d |
||
---|---|---|---|---|---|
M | F | M | F | ||
SERUM | |||||
Glucose | mg/dl | 115 ± 16.9 | 111 ± 17.2 | 115 ± 12.5c | |
Urea nitrogen | mg/dl | 19 ± 2.2 | 21 ± 3.4 | 15 ± 2.5c | |
Creatinine | mg/dl | 0.70 ± 0.11 | 0.70 ± 0.13 | ||
Sodium | mEq/l | 150 ± 3.4 | 148 ± 3.5 | 149 ± 3.0c | |
Potassium | mEq/l | 7.00 ± 0.65 | 6.1 ± 0.67 | 4.80 ± 0.35c | |
Chloride | mEq/l | 103.0 ± 1.90 | 104.0 ± 2.4 | 106 ± 3.0c | |
Calcium | mg/dl | 12.0 ± 0.94 | 12.1 ± 0.71 | 10.5 ± 0.50c | |
Phosphorus | mg/dl | 7.30 ± 1.5 | 5.80 ± 1.10 | ||
Magnesium | 3.12 ± 0.41e | 2.60 ± 0.21e | |||
Iron | μg/dl | 152 ± 70 | 220 ± 130 | ||
(19–21 weeks) | |||||
Total iron-binding capacity | μg/dl | 368c | |||
Alanine aminotransferase | IU/l | 49 ± 24.1 | 69 ± 44.9 | 78 ± 11 | 49 ± 8 |
Aspartate aminotransferase | IU/l | 95 ± 31.7 | 99 ± 54.5 | ||
Alkaline phosphatase | IU/l | 130 ± 43.7 | 117 ± 41.7 | 49.5 ± 9.25c | |
Lactate dehydrogenase | IU/l | 275 ± 112 | 650 ± 75 | 650 ± 75 | |
(20 weeks) | |||||
Sorbitol dehydrogenase | IU/l | 20 ± 5c | 20.0 ± 7.5c | ||
(32 weeks) | |||||
γ-Glutamyl transpeptidase | IU/l | 2.5 ± 1.25c | |||
Creatinine kinase | IU/l | 275 ± 112.5c | 400 ± 50c | ||
Protein, total | g/l | 70 ± 5.0 | 75 ± 5 | 70.5 ± 4.75c | |
Albumin | g/l | 34 ± 2.0 | 40 ± 2.5 | 42.5 ± 3.75c | |
Cholesterol | mg/dl | 119 ± 51.3 | 119 ± 29.0 | 96.5 ± 14.25 | 130 ± 10.0 |
Triglycerides | mg/dl | 266 ± 121.4 | 249 ± 159.7 | 122 ± 21.25 | 62.5 ± 11.25 |
Bilirubin | mg/dl | 0.3 ± 0.16 | 0.4 ± 0.27 | 0.3 ± 0.1c | |
Bile acids | μmol/l | 40 ± 10c | 30 ± 10c | ||
(20 weeks) | |||||
Uric acid | mg/dl | 1.52 ± 0.30 | 1.25 ± 0.36 | ||
URINE | |||||
Volume | ml/16 h | 9.5 ± 4.0 | 9.3 ± 5.6 | ||
ml/22 h | 15.7 ± 6.7 | 11.0 ± 5.0 | |||
Specific gravity | 1.022 ± 0.007 | 1.017 ± 0.007 | |||
Osmolality | mOsm/kg | 943 ± 327 | 995 ± 367 | ||
pH | 7.8 ± 0.5 | 7.7 ± 0.5 | 6.0–6.5c | ||
Chloride | mmol/l | 148 ± 36 | 151 ± 51 | ||
Sodium | mmol/l | 31 ± 11 | 50 ± 22 | ||
Potassium | mmol/l | 121 ± 31 | 110 ± 45 | ||
Phosphorus | mg/dl | 142 ± 34 | 156 ± 62 | ||
Creatinine | mg/dl | 136 ± 40 | 116 ± 41 | 80 ± 28 | 54 ± 25 |
Glucose | mg/dl | 9.9 ± 3.9 | 5.5 ± 2.3 | ||
Protein | mg/dl | 98.8 ± 54.4 | 11.2 ± 5.5 | ||
Alkaline phosphatase | IU/l | 152 ± 61 | 73 ± 37 | ||
Lactate dehydrogenase | IU/l | 28 ± 15 | 16 ± 8 | ||
N-Acetyl-β-glucosaminidase | IU/l | 12.2 ± 7.8 | 5.9 ± 2.7 | ||
Aspartate aminotransferase | 14.4 ± 6.5 | 3.6 ± 2.5 | |||
γ-Glutamyl transpeptidase | IU/l | 4964 ± 780 | 1873 ± 215 | ||
Insulin clearance | μl/min/100 g | 857 ± 178 | |||
Glomerular filtration rate | μl/min | 275 ± 33c | |||
Urine flow | μl/min/100 g | 5.2 ± 2.0 |
Values are for 12-month-old animals, unless noted otherwise, as summarized from Loeb and Quimby (1999).
6–18 months old.
Gender not specified.
58–l 12 weeks old.
Wistar strain.