Table 4.5.
Hematological Parameters in the Rata
| Parameter (units) | Stock/Strain |
|||||
|---|---|---|---|---|---|---|
| Crl:CD(SD) |
Crl:LE |
F344/DuCRL |
||||
| Male | Female | Male | Female | Male | Female | |
| WBC (K/μl) | 11 (4.0–18) | 9.5 (2.4–18) | 9.8 (5.6–14) | 8.7 (4.9–13) | 6.7 (2.1–9.6) | 7.4 (1.9–12) |
| Neutrophils (K/μl) | 3.4 (1.0–6.7) | 2.6 (0.7–5.9) | 4.0 (2.2–6.5) | 3.2 (1.7–5.4) | 2.5 (0.7–3.9) | 2.4 (0.5–4.4) |
| Lymphocytes(K/μl) | 6.5 (2.2–12) | 6.1 (1.5–11.5) | 5.0 (2.5–7.9) | 4.6 (2.6–7.9) | 3.6 (1.0–5.7) | 4.4 (1.2–7.5) |
| Monocytes (K/μl) | 0.7 (0.2–1.4) | 0.6 (0.1–1.2) | 0.7 (0.3–1.2) | 0.7 (0.3–1.3) | 0.5 (0.1–1.0) | 0.5 (0.1–1.0) |
| Eosinophils (K/μl) | 0.1 (0–0.5) | 0.1 (0–0.5) | 0.1 (0–0.5) | 0.2 (0–0.8) | 0.1 (0–0.3) | 0.1 (0–0.5) |
| Basophils (K/μl) | 0.03 (0–0.2) | 0.03 (0–0.2) | 0.03 (0–0.1) | 0.04 (0–0.3) | 0.02 (0–0.1) | 0.03 (0–0.1) |
| Neutrophils (%) | 32 (16–54) | 28 (14–55) | 41 (30–51) | 38 (25–51) | 37 (25–53) | 32 (19–47) |
| Lymphocytes (%) | 61 (38–79) | 63 (37–81) | 51 (41–63) | 53 (38–65) | 54 (40–67) | 59 (42–74) |
| Monocytes (%) | 6.3 (3–11) | 6.5 (3–11) | 6.6 (3–10) | 7.4 (4–12) | 7.6 (7.7–12) | 6.8 (2.9–12) |
| Eosinophils (%) | 1.2 (0.1–4.3) | 1.4 (0.2–4.8) | 1.2 (0.1–4.1) | 1.6 (0.1–7.3) | 0.9 (0–3.7) | 1.6 (0.1–5.5) |
| Basophils (%) | 0.3 (0–1.7) | 0.3 (0–1.6) | 0.3 (0–1.6) | 0.4 (0–2.4) | 0.4 (0–1.1) | 0.4 (0–1.3) |
| RBC (M/μl) | 7.7 (5.8–10) | 7.4 (5.5–9.8) | 7.6 (6.0–9.4) | 7.6 (6.7–8.6) | 8.3 (7.1–9.7) | 8.1 (6.6–9.4) |
| Hemoglobin (g/dl) | 17 (13–23) | 16 (13–22) | 16 (13–20) | 16 (14–18) | 16 (14–19) | 16 (13–18) |
| Hematocrit (%) | 51 (39–69) | 48 (37–64) | 52 (43–62) | 51 (43–60) | 54 (47–62) | 54 (44–62) |
| MCV (fl) | 67 (58–77) | 66 (58–75) | 69 (63–76) | 67 (61–75) | 65 (60–69) | 67 (63–70) |
| MCH (pg) | 22 (17–25) | 22 (18–25) | 21 (19–24) | 21 (20–23) | 20 (17–22) | 20 (17–22) |
| MCHC (g/dl) | 33 (27–38) | 33 (27–38) | 31 (29–33) | 31 (29–43) | 31 (27–34) | 30 (26–32) |
| RDW (%) | 16 (14–18) | 15 (13–17) | 16 (13–17) | 14 (12–15) | 15 (14–17) | 13 (12–15) |
| Platelets (M/μl) | 1.6 (0.8–2.6) | 1.6 (0.8–2.4) | 1.4 (0.7–1.9) | 1.3 (0.6–1.7) | 1.1 (0.8–1.6) | 1.1 (0.7–1.5) |
| MPV (fl) | 7.4 (5.9–10) | 7.3 (5.8–9.6) | 8.0 (6.7–9.2) | 8.1 (5.8–9.5) | 6.9 (5.8–8.2) | 6.8 (5.7–8.1) |
a
Derived from vendor data (Charles River Research Models) on animals 8–10 weeks of age; mean (95% confidence interval).