Table 3.
Relationship Between Clinicopathological Factors and PT/Fbg System Score.
| Variables | PT/Fbg System Score, No. (%) | |||
|---|---|---|---|---|
| Score 0, 187 (29.78) | Score 1, 305 (48.57) | Score 2, 134 (21.44) | P Value | |
| Gender | ||||
| Male | 171 (91.44) | 265 (86.89) | 123 (91.79) | .163 |
| Female | 16 (8.56) | 40 (13.11) | 11 (8.21) | |
| Age (years) | ||||
| <53 | 90 (48.13) | 135 (44.26) | 69 (51.49) | .350 |
| ≥53 | 97 (51.87) | 170 (55.74) | 65 (48.51) | |
| TNM stage | ||||
| I | 122 (65.24) | 159 (52.13) | 36 (26.86) | <.001 |
| II | 34 (18.18) | 64 (20.98) | 25 (18.66) | |
| III | 22 (11.76) | 47 (15.41) | 44 (32.84) | |
| IV | 9 (14.82) | 35 (11.48) | 29 (21.64) | |
| T stage | ||||
| T1-2 | 159 (85.03) | 232 (76.07) | 65 (48.51) | <.001 |
| T3-4 | 28 (14.97) | 73 (23.93) | 69 (51.49) | |
| Node stage | ||||
| N0 | 182 (97.33) | 289 (94.75) | 114 (85.07) | <.001 |
| N1-2 | 5 (2.67) | 16 (5.25) | 20 (14.93) | |
| Distant metastases | ||||
| No | 181 (96.79) | 291 (95.41) | 125 (93.28) | .337 |
| Yes | 6 (3.21) | 14 (4.59) | 9 (6.72) | |
| Treatment | ||||
| Resection | 111 (59.36) | 148 (48.52) | 46 (34.33) | <.001 |
| Local ablation | 26 (13.90) | 49 (16.07) | 8 (5.97) | |
| Interventional therapy | 40 (21.39) | 97 (31.80) | 64 (47.76) | |
| Other | 10 (5.35) | 11 (3.61) | 16 (11.94) | |
| ECOG | ||||
| 0-1 | 182 (97.33) | 296 (97.05) | 133 (99.25) | .364 |
| 2 | 5 (2.67) | 9 (2.95) | 1 (0.75) | |
| Alcohol behavior | ||||
| Never | 112 (59.89) | 196 (64.26) | 81 (60.45) | .570 |
| Previous/current | 69 (36.90) | 102 (33.44) | 51 (38.06) | |
| Family history of cancer | ||||
| No | 139 (74.33) | 243 (79.67) | 103 (76.87) | .569 |
| Yes | 41 (21.93) | 57 (18.69) | 29 (21.64) | |
| HBs Ag | ||||
| Negative | 17 (9.09) | 59 (19.34) | 14 (10.45) | .001 |
| Positive | 113 (60.43) | 173 (56.72) | 93 (69.40) | |
| HBe Ag | ||||
| Negative | 118 (63.10) | 203 (66.55) | 91 (67.91) | .181 |
| Positive | 12 (6.42) | 29 (9.51) | 16 (11.94) | |
| HBc Ab | ||||
| Negative | 124 (66.31) | 203 (66.56) | 100 (74.63) | .025 |
| Positive | 6 (3.21) | 29 (9.51) | 7 (5.22) | |
| LSR | ||||
| ≥1.065 | 51 (27.27) | 123 (40.33) | 65 (48.51) | <.001 |
| <1.065 | 136 (72.73) | 182 (59.67) | 69 (51.49) | |
| GPS | ||||
| 0 | 178 (95.19) | 224 (73.44) | 35 (26.12) | <.001 |
| 1 | 8 (4.28) | 75 (24.59) | 70 (52.24) | |
| 2 | 1 (0.53) | 6 (1.97) | 29 (21.64) | |
Abbreviations: GPS, Glasgow Prognostic Score; HBs Ag, hepatitis B surface antigen; HBe Ag, hepatitis B e-antigen; HBc Ab, hepatitis B core antibody; LSR, ALT/AST ratio; PT/Fbg, prothrombin time and fibrinogen.