FIG 6.

Minigenome reporter assay using mutagenized VSV L and P. (A and B) Using a minigenome reporter system, the effects of alanine substitutions or residue deletion in VSV L (A) and P (B) on reporter activity were quantified and compared against the wild-type (PosCon) sample. Error bars represent standard deviations (SD) for n = 3, and asterisks denote a significant difference (P < 0.05) of the sample relative to WT in a two-tailed t test. (C) Western blots against wild-type and mutagenized P are provided for each sample, along with a control blot against glyceraldehyde 3-phosphate dehydrogenase (GAPDH).