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. 2020 Feb 28;94(6):e01883-19. doi: 10.1128/JVI.01883-19

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Copyright © 2020 Ringe et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 4 — Antigenicity of B41 SOSIP.v4.1-KG4 IO-NP trimers by NAb depletion assay. (A) bNAb VRC01 or rabbit MAb 16D was incubated without (▲) or with (●) B41 SOSIP.v4.1-KG4 IO-NP trimers or with control, uncoupled IO-NPs (■), before assessing B41 virus neutralization. (B) As in panel A, except that rabbit anti-B41 SOSIP.v4.1 trimer serum samples r2428 and r2449 were used. (C) As in panel A, except that the MAbs were 17b and 19b and the test virus was MW965.26. This experiment was performed at DUMC.