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. 2020 Feb 28;94(6):e01883-19. doi: 10.1128/JVI.01883-19

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Copyright © 2020 Ringe et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG A4 — Antigenicity of BG505 SOSIP.v4.1-KG4 IO-NP trimers by an NAb depletion assay. (A) bNAb VRC01 or rabbit MAb 10A was incubated without (▲) or with (●) BG505 SOSIP.v4.1-KG4 trimer IO-NPs or with control, uncoupled IO-NPs (■) before testing for BG505.T332N virus neutralization. (B) As in panel A, except that rabbit anti-BG505 SOSIP.664 trimer serum samples r5724 and r5725 were used. (C) As in panel A, except that bNAb VRC01 and rabbit serum sample r5725 was used and the test virus was MW965.26. This experiment was performed at WCMC.