FIG A8.

Relative intrinsic affinities of mouse serum anti-trimer antibodies. Correlation between ELISA binding and neutralization titers. Mouse IgG from bleed 5 was titrated against the B41 SOSIP.v4.1-His trimer captured at 1.5 μg/ml (HAg assay; black squares) or 0.2 μg/ml (LAg assay; red circles). The resulting endpoint titers are plotted on the y axis against the B41 neutralization titers (Fig. 7A) on the x axis. The r and P values of the Spearman correlations for the two comparisons are recorded.